Meat Casserole Recipes: Mac And Cheese Meatloaf for Potlucks

Created on February 6th, 2026 at 10:37 am

A Shareable, Sliceable Casserole Designed for Group Gatherings

Mac and cheese meatloaf casserole is built for potlucks where food needs to travel well, serve easily, and satisfy a wide range of tastes. This recipe combines a savory ground beef meatloaf base with a creamy macaroni and cheese layer baked together into a single casserole that slices cleanly and holds its structure on a buffet table. The goal is not novelty but reliability. Every slice delivers familiar flavors, balanced textures, and enough richness to feel special without being overwhelming.
Potluck-style dishes work best when they are stable and predictable. This casserole is designed to be assembled ahead, baked in one dish, and served warm or at room temperature without losing its appeal. The meatloaf layer provides structure and protein, while the mac and cheese layer adds comfort and visual appeal. Together, they form a dish that feels appropriate for casual gatherings, shared tables, and events where food needs to be both hearty and approachable.
Unlike loose casseroles that can fall apart after serving, this mac and cheese meatloaf casserole is intentionally structured. The layers bake together so they support each other, allowing the casserole to be cut into neat portions that stay intact. This makes it especially practical for potlucks, where clean serving and consistent portions matter.

Why This Mac And Cheese Meatloaf Works for Potlucks

Potluck recipes succeed when they meet three criteria: they hold heat well, they serve easily, and they appeal to many palates. This casserole meets all three. The meatloaf base absorbs moisture from the macaroni layer, preventing dryness even after sitting out for a short time. The mac and cheese layer stays creamy without becoming soupy, which helps the casserole maintain its shape.
The flavor profile is intentionally familiar. Mild seasoning, classic cheese, and a simple meatloaf base ensure that the dish is crowd-friendly. This makes it a reliable choice when cooking for mixed groups, including children and adults with different preferences. Because the casserole does not rely on delicate textures or crisp toppings, it performs well in buffet-style settings.

Flavor and Texture Expectations

The meatloaf layer should be tender, savory, and evenly cooked, with enough firmness to support the pasta above it. Breadcrumbs and milk create a soft interior, while baking allows excess moisture to evaporate gradually.
The mac and cheese layer should be creamy and cohesive, not loose. The cheese sauce is designed to coat the pasta fully, creating a smooth layer that sets gently during baking. When sliced, the layers should remain distinct but connected, producing clean portions that do not collapse.
Overall, the texture should feel comforting and substantial, with no part of the casserole feeling dry, greasy, or overly dense.

Time Breakdown

Prep time: 30 minutes
Cook time: 45 minutes
Total time: About 1 hour 15 minutes

Ingredients

Meatloaf Layer

1. 1 1/2 pounds ground beef
2. 3/4 cup breadcrumbs
3. 1/2 cup milk
4. 2 large eggs
5. 1/2 cup finely chopped onion
6. 2 cloves garlic, minced
7. 1 teaspoon salt
8. 1/2 teaspoon black pepper
9. 1 teaspoon Italian seasoning
10. 2 tablespoons ketchup
    Mac And Cheese Layer
11. 8 ounces elbow macaroni
12. 2 tablespoons butter
13. 2 tablespoons all-purpose flour
14. 2 cups milk
15. 1 1/2 cups shredded cheddar cheese
16. 1/2 cup shredded mozzarella cheese
17. 1/2 teaspoon salt
18. 1/4 teaspoon black pepper

Kitchen Tools

• Large mixing bowl
• Measuring cups and spoons
• Large pot
• Colander
• Saucepan
• Whisk
• 9×13-inch baking dish
• Spoon or spatula

Step-by-Step Instructions

1. Preheat the oven to 375°F and lightly grease a 9×13-inch baking dish to ensure the casserole releases cleanly after baking.
2. In a large mixing bowl, combine breadcrumbs and milk and let sit for 1 to 2 minutes until softened. This step helps keep the meatloaf tender.
3. Add ground beef, eggs, chopped onion, minced garlic, salt, black pepper, Italian seasoning, and ketchup to the bowl.
4. Mix gently just until combined, avoiding overmixing to prevent a dense texture.
5. Press the meatloaf mixture evenly into the bottom of the prepared baking dish, smoothing the surface so it cooks evenly.
6. Bring a large pot of salted water to a boil and cook the macaroni until just al dente according to package directions.
7. Drain the macaroni well and set aside so excess moisture does not thin the cheese sauce.
8. In a saucepan over medium heat, melt the butter, then whisk in the flour and cook for about 1 minute until smooth.
9. Slowly whisk in the milk, stirring constantly, and cook until the sauce thickens enough to coat the back of a spoon.
10. Reduce the heat and stir in the cheddar and mozzarella until fully melted and smooth. Season with salt and black pepper.
11. Add the cooked macaroni to the cheese sauce and stir until evenly coated.
12. Spoon the mac and cheese evenly over the meatloaf layer, spreading gently to keep the layers distinct.
13. Bake uncovered for about 45 minutes, or until the meatloaf is fully cooked and the top is lightly set.
14. Remove the casserole from the oven and let rest for 10 minutes so the layers firm slightly.
15. Slice into portions and serve warm.

Serving Suggestions for Potlucks

Serve this casserole directly from the baking dish for easy sharing. It pairs well with simple salads, steamed vegetables, or roasted sides that balance the richness. Because it holds its structure well, it can be served with a spatula without falling apart, making it ideal for buffet-style tables.

Storage and Make-Ahead Tips

This casserole can be assembled up to 24 hours in advance, covered, and refrigerated before baking. If baking from cold, add 5 to 10 minutes to the cooking time.
Leftovers can be stored in airtight containers in the refrigerator for up to 3 days. Reheat covered to maintain moisture.

Nutrition Information (Approximate)

Nutrient	Amount
Calories	620
Carbohydrates	42 g
Protein	34 g
Fat	36 g
Fiber	3 g
Sugar	5 g
Sodium	890 mg

Disclaimer: Nutrition facts are estimated using online tools and may vary based on your ingredients and preparation. Please consult a nutritionist for precise dietary advice.

Frequently Asked Questions

Can I make this casserole the day before a potluck?
Yes. Assemble the casserole fully, cover tightly, and refrigerate. Bake it shortly before serving or reheat gently before the event.
Will this hold up on a buffet table?
Yes. The structured layers help it stay intact and appealing even after sitting out for a short time.
Can I double this recipe for a large group?
Yes. Prepare two casseroles rather than one very large dish to ensure even cooking.
Does this freeze well?
Yes. Cool completely, wrap tightly, and freeze for up to 2 months. Thaw overnight before reheating.
What makes this good for potlucks?
It slices cleanly, travels well, and uses familiar flavors that appeal to a wide range of guests.